Denise Faustman, MD, PHd
The Faustman Lab at work

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Other Autoimmune Research

In addition to our research program in type 1 diabetes, the Faustman Lab also performs other, related autoimmune disease research.

Much like in type 1 diabetes, data suggests that the disease-causing cells in Sjögren’s syndrome, rheumatoid arthritis, lupus, Crohn’s disease, and multiple sclerosis may be eliminated when exposed to higher-than-usual levels of tumor necrosis factor (TNF), a key signaling protein in the immune system. The Lab investigates these connections. As part of this research, we are currently conducting studies to improve the diagnosis of Sjögren’s syndrome.

Sjögren’s Syndrome Fast Diagnosis Project 
The Faustman Lab’s Sjögren’s Syndrome Fast Diagnosis Project is investigating methods to improve the diagnosis of Sjögren’s syndrome.

Today, it is difficult to accurately and quickly diagnose Sjögren’s syndrome. Syndrome symptoms are often confused for symptoms of other conditions, and patients can spend years going from one specialist to the next before they get the correct diagnosis. In addition, diagnosis can involve a lip biopsy, which is invasive and can be inconclusive.

The Faustman Lab is developing a simple blood test to quickly and accurately diagnose Sjögren’s syndrome. We would be happy to set up an appointment for you to contribute a blood sample at our facility in Boston. If you are interested in participating in this research study, please contact us by phone at 617-726-4084 or by email at You can also begin by filling out the patient registration form and faxing, emailing, or mailing it back to us. All testing is free.